As an interventional cardiologist Dr. Roger H. Coletti recognized the true nature of atrophic myofibers described in biopsies harvested from horses suffering spams syndrome: that they were not "denervated muscle fibers", but "hibernating skeletal muscle fibers", which can become triggers for chronic pain.

These new concepts explain why treating chronic muscle spasm in skeletal muscles with BOTOX or other pharmacological inhibitors of neuromuscular synaptic function which includes phenoxybenzamine, can relieve muscle spasm and pain.

In this book there is much more compelling evidence of the true nature of simple muscle atrophy in case of muscle spasm, and on the progressive clarification of diagnosis and treatment of chronic cases of low back pain induced by muscle spasms.

His experience is based on well over 200 patients, a population that provides strong preliminary data useful for independent confirmation of his new concepts and management of chronic low back pain and chronic pain from other sites associated with chronic muscle spasm.

Ugo Carraro - Senior Scholar of Padua University

Editor-in-Chief, European Journal of Translational Myology

Department of Biomedical Sciences, University of Padua, Italy

About the Author

Roger H. Coletti, MD, FACC, FASNC, FSCAI is an interventional cardiologist with a long-standing interest in chronic muscle spasm. Over the past 15 years he was able to develop a simple, successful and durable treatment for chronic muscle spasm and the resultant chronic pain. In the process he was able to discover the direct cause of chronic muscle spasm and proposed an ischemic model to explain the electrical abnormalities and pathophysiological tissue changes. He has written this book to chronicle these advances and make available to physicians a stepwise instruction manual for use of his CMECD© procedure.